Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISMKVVFHIDELEKWSETGKNVKNLIKASPE-----TTIVVSVNGIAI----------TGYLDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVI---------VVPAGVLDLVELQSQGYAYIKP 2D1P Chain:A ((11-140)) -GSMRFAIVVTGPAYGTQQASSAFQFAQALIADGHELSSVFFYREGVYNANQLTSPASDEFDLVRAWQQLNAQHGVALNICVAAALRRGVVDETEAGRLGLASSNLQQGFTLSGLGALAEASLTCDRVVQF

General information: TITO was launched using: RESULT: Template: 2D1P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 431 -26411 -61.28 -249.16 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -61.28 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.357

(partial model without unconserved sides chains): PDB file : Tito_2D1P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2D1P-query.scw PDB file : Tito_Scwrl_2D1P.pdb: