Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------MEWMRFFDNRINYDILITKRKRILSVGGRKVKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDALQFGKKGRGKRKNLLALSRNMWIGTEVTI---EADGTVFINGKDRYTPEELWYKGKKSIPEL---------------- 3QH6 Chain:A ((1-153)) SRMRAVLHLEHKRYFQNH--GHILFEGL-----APVSDCKQLEAELKLFLWRENVHRTLP-----GVQMIVKRVRLDHLAAELT--------HRSRVALVRDLWVQKQEEILFDDCDCSVLLCLSGEKAGWGLFFSGEYPQDVFDWGAGDTAIILRFSSA

General information: TITO was launched using: RESULT: Template: 3QH6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 385 13882 36.06 122.85 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 36.06 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.215

(partial model without unconserved sides chains): PDB file : Tito_3QH6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QH6-query.scw PDB file : Tito_Scwrl_3QH6.pdb: