Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNDF--------TTEIMEILIN-----KGDLDDLFRRHLELAINALLQAELTVFL----DYEKYDRAGFNSGNSRNGNY------SRSFKTEYGELNLVIP----RDRNGDFSQQTLPAYKRTNDSLETTIIQLVQKG-------ITMSEISDLIEK-----MYGHYYKP--------QTISNMSKIVSE----DVSAFKERTLEAKYSVIFMDATHIPLKRQTVSKEAVYIVIG---IRLDGTKEVLGFTIAPTESAYVWKEILQDLKDRGLEEVLLVVTDGLSGID---------DSIHSVYPNAQFQQCCVHISRN-IAHKVRVSDR-QEICSDFKLVY------------QASSKEEANNQIR-----FMIDKWKKQYPRVVKLLM------NPAILT-FYNFPPSIRRTIY-----STNLIEGFNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF 5DXF Chain:B ((18-528)) PKEFEGKGKLKLSGRILNVMTSLPLQIVRGNSALYSSQHFLAENKEWETHLIAWTGDEEDKSKIEKKLCDASGTPNIHPVWLLRRDQGRWRKYAENVLWPVFHYIQPSDGKAETDAWHDYVKFNEAYLNKIKSVYKPGDIIWIHDYYLLLLPQLLRMEFPNAYIGFFLHVPFPSSEYFRCLSKRSQLLDGMLGADKIGFQSDSFQRHFISCCARVLGCEVNRDSVSAYGTTISVETLPIGIDTEKIEHDAF----SSELGVEEKVQALKQVYKGKKLIVGRDRLDKVRGVIQKLEGFEIFLDMYPEWRETVVLIQVSSPGYSHSANVETRVTEIISRINSKYGNLNHTPVLHYQMRVAKEEYLALLRVADLALITSVRDGMNTTSLEFVICQKYNNSPLILSEFTGTATVLKDAIMVNPWDSVGVAKTINDALMLSTKEKVSL-ESKLYEKVLSNTVQNWTSTFICDILSHSI----------

General information: TITO was launched using: RESULT: Template: 5DXF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1694 63430 37.44 169.60 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : 37.44 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.213

(partial model without unconserved sides chains): PDB file : Tito_5DXF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DXF-query.scw PDB file : Tito_Scwrl_5DXF.pdb: