Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -----KESYKVKKICHYSIQKLHGKTWYQVGTGQADAGKD-THIEGTKVFFSNQCLPQWNNRRLYIKLDSE-------EVVPV 1YEZ Chain:A ((1-68)) MFREESRSVPVEE----------GEVYDVTIQDIARQGDGIARIEGFVIFVPG-TKV---GDEVRIKVERVLPKFAFASVVE-

General information: TITO was launched using: RESULT: Template: 1YEZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 163 7475 45.86 135.90 target 2D structure prediction score : 0.80 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 45.86 2D Compatibility (Sec. Struct. Predict.) : 0.80 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.469

(partial model without unconserved sides chains): PDB file : Tito_1YEZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YEZ-query.scw PDB file : Tito_Scwrl_1YEZ.pdb: