Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKFRIDLLRHGESQY--SHTLRGHLDDELTAKGWQQMQATIEQVSN--QPWDVIVSSSLKRCVCFAEQLAKTAELPLLVNHDLKEMYFGEWEGISTQQIYETSPELLANFWQKPSQYCPPRAETLDQFQTRVLKGFQDLLEHMQKQNLQHALVVTHGGVIKLLACLARQQPLDDLLKMPAELGKLYSLEFSETDSQLTFKLR 2A6P Chain:B ((9-189)) -RNHRLLLLRHGETAWSTLGRHTGGTEVELTDTGRTQAELAGQLLGELELDDPIVICSPRRRTLDTAKLAGLTV---NEVTGLLAEWDYGSYEGLTTPQIRESEPD-WLVW-----THGCPAGESVAQVNDRADSAVALALEHM---SSRDVLFVSHGHFSRAVITRWVQLPLAEGSRFAMPTASIGICGFEHG---------

General information: TITO was launched using: RESULT: Template: 2A6P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 962 -5448 -5.66 -30.78 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.69 3D Compatibility (PKB) : -5.66 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.454

(partial model without unconserved sides chains): PDB file : Tito_2A6P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2A6P-query.scw PDB file : Tito_Scwrl_2A6P.pdb: