Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSNIYQFEAELLVGDIKQFADYKGKVLLIVNTASKCGFTP-QFAGLEKLYEKYKDLGLEVLGFPCNQFGGQDPGSNKEIGTFCQRNYGVKFPMFAKVDVKGPEAHVIFRYLTRE-------AKGILGSSTIKWNFTKFLVGKDGSVLNRYAPTTKPEALEADIEKALAS 5H5R Chain:A ((11-168)) -RSMHEFSAKDIDGHMVNLDKYRGFVSIVTNVASQ-GKTEVNYTQLVDLHARYAERGLRILAFPSNQFGKQEPGSNEEIKEF-AAGYNVKFDMFSKIEVNGDDAHPLWKWMKIQPKGKGILGNAIKWN------FTKFLIDKNGVVVKRYGPMEEPLVIEKDLPHY---

General information: TITO was launched using: RESULT: Template: 5H5R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 746 6085 8.16 40.84 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : 8.16 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.579

(partial model without unconserved sides chains): PDB file : Tito_5H5R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5H5R-query.scw PDB file : Tito_Scwrl_5H5R.pdb: