Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---WDLLPSAEQVGKLVPSAEQIGKWVLSKEQIDALFFYQCQVTIHYPGAERGKLLKYL-AEPREPIPLPKFQGK--LYYAISDSGCKYREYSKGDPWPKGLKQMDCFFGPRCTAIGKRKIVLQV------------ 1C44 Chain:A ((1-123)) SSAGDGFKANLVFKEIEKKLEEEGEQFVKK--IGGIFAFKVKDG---PGGKEATW--VVDVKNGKGSVLPNSDKKADCTITMADSD--LLALMTGK-----MNPQSAFFQGKLKITGNMGLAMKLQNLQLQPGKAKL

General information: TITO was launched using: RESULT: Template: 1C44.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 434 21701 50.00 206.67 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 50.00 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.376

(partial model without unconserved sides chains): PDB file : Tito_1C44.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1C44-query.scw PDB file : Tito_Scwrl_1C44.pdb: