Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRLDIHLNFIKRLSSMNKEIFKIINPSTLYDPTPNAYSHVAVVSNFNNIIHIAGQGGEDQQ-GQLSSHFSEQVLQTFENINYALVAANAELTDIAVLRILVVDHSVEKHEILIKIMKDLWKNH--PFPACTLIPVPRLALEHMLIEVEATAYT 1QU9 Chain:B ((4-127)) ----------------------TIATENAPAA-IGPYVQGVDL---GNMIITSGQIPVNPKTGEVPADVAAQARQSLDNVKAIVEAAGLKVGDIVKTTVFVKDLND--FATVNATYEAFFTEHNATFPARS-VEVARLP-KDVKIEIEAIAVR

General information: TITO was launched using: RESULT: Template: 1QU9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 566 -12362 -21.84 -103.02 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.70 3D Compatibility (PKB) : -21.84 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.384

(partial model without unconserved sides chains): PDB file : Tito_1QU9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QU9-query.scw PDB file : Tito_Scwrl_1QU9.pdb: