Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHTSTTSTVPLEPWIAQQLQQATQGYWHKDQIPQSEIKRILTDSRHAESGDAFLALKGERFDAHNFVAQVAANGCQVAIVERPIDAEIAQLVVAD-----TRLALGQLGAYRREQNAQLKVIALTGSSGKTTTKEMLGSILSRLAP-TLINRGNLNNDLGVPMMLLELRKEHQYAVMELGANHQGEIDYTSKIVQPHVAGILNIGTAHLGEFG-GRDGICRAKSEIYRHILPQGVAIVPQQDDFTAEIREAAKSHQIMSFGAG--GDVFATEIELLPQSANFQLHTPQ-GSSFVRLPFAGEHNVQNATAAVAFALALGVSLEDIVKGLEQAQGAKGRLNFIQ-----KAPHLFIDDTYNANPTSMRAAAQVLLQ-QNGIKV-MVMGDIGELGDSSWQEHHDLGRDLAGLPLDHIVAV-----------GQFASAALEGAGLHS-TKLKAFQTQAEALPFLINLIQTHQ-PQSMSFLFKGSRFTHM--ETLMADLMEKL 1GQY Chain:B ((76-473)) ------------------------------------------------------------------------EGASVVVVSSAIKDDNPELVTSKQKRIPVIQRAQMLAEIM----RFRHGIAVAGTHGKTTTTAMISMIYTQAKLDPTFVNGG----LVKSAGKNAHLGASRYLIAEADESDA-----SFLHLQPMVSVVTNMEPDHMDTYEGDFEKMKATYVKFLHNLPFYGLAVMCADDPVLMELVPKV-GRQVITYGFSEQADYRIEDYEQTGFQGHYTVICPNNERINVLLNVPGKHNALNATAALAVAKEEGIANEAILEALADFQGAGRRFDQLGEFIRPNGKVRLVDD-YGHHPTEVGVTIKAAREGWGDKRIVMIFQP-HRYSRTR-DLFDDFVQVLS-Q-VDALIMLDVYAAGEAPIVGADSKSLCRSIRNLGKVDPILVSDTSQLGDVLD-----QIIQDGDLILAQGAGSVSKISRGLAESW----

General information: TITO was launched using: RESULT: Template: 1GQY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1870 -15854 -8.48 -43.32 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain B : 0.67 3D Compatibility (PKB) : -8.48 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.372

(partial model without unconserved sides chains): PDB file : Tito_1GQY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GQY-query.scw PDB file : Tito_Scwrl_1GQY.pdb: