Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVIALFSKNWSRTMSATIVNTTDDNFQADVLDAETPVLVDFWAGWCAPCKAIAPVLEDLSSEYAGKVKIVKVDVTSCEETAVKYNIRNIPALLLFKNGEVVAQQIGAVPRSKLVSFIDENV 2H72 Chain:B ((1-107)) --------------SDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGDVAATKVGALSKGQLKEFLDANL

General information: TITO was launched using: RESULT: Template: 2H72.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 477 -86590 -181.53 -809.25 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : -181.53 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.871

(partial model without unconserved sides chains): PDB file : Tito_2H72.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H72-query.scw PDB file : Tito_Scwrl_2H72.pdb: