Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEEKKMKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGVAAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFLAKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGVDNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTEDSVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFEVGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRV---LGVAGGSMVRAN-QSGIIDVGPRSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANVLGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKYHLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERIIPSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSK-VTAIATGSTEVKATDLTKEITTE-EALELAAEDMRLNKNEVCLLENTPFFYVC-----GEQNRSKNAGSLRIIDQKGFIKVQRGHASCMKTTAANYMTA----VEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQLQLLMDLEVSTM---EPEEEVIVVAGNIKQT---------- 1E7P Chain:A ((1-655)) MKVQYCDSLVIGGGLAGLRAAVATQQKGLSTIVLSLIPVKRSH--SAAAQGGMQASLGNSKMSDG---DNEDLHFMDTVKGSDWGCDQKVARMFVNTAPKAIRE--LAAWGVPWTRIHKGDRMAI---------------INAQKTTITEEDFRHGLIHSRDFG--GTKKWRTCYTADA--------------------------TGHTMLFAVANECLKLGVSIQDRKEAIALIHQDGKCYGAVVRDLVTGDIIAYVAKGTLIATGGYGRIYKNTTNAVVCEGTGTAIALETGIAQLGNMEAVQFHPTPLFPSGILLTEGCRGDGGILRDVDGHRFMPDYEPEKKELASRDVVSRRMIEHIRKGK-----GVQSPYGQHLWLDISILGRKHIETN-----LRDVQEICEYFAGIDPAEKWAPVLP-MQHYSMGGIRTDYRGEA--------------------KLKGLFSAGEAACWDMHGFNRLG-GNSVSEAVVAGMIVGEYFAEHCANTQVDLETKTLEKFVKGQEAYMKSLVESKGTEDVFKIKNRMKDVMDDNVGIFRDGPHLEKAVKELEELYKKSKNVGIKNKRLHANPELEEAYRVPMMLKVALCVAKGALDRTESRGAHNREDYP-----KRDDINWLNRTLASWPNPEQTLPTLEYEALDVNEMEIAPGYRGYGAKGNYIENPLSVKRQEEIDKIQSELEAAGKDRHAIQEALMPYELPAKYKARNERLGD

General information: TITO was launched using: RESULT: Template: 1E7P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 4055 -29011 -7.15 -46.27 target 2D structure prediction score : 0.36 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -7.15 2D Compatibility (Sec. Struct. Predict.) : 0.36 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.152

(partial model without unconserved sides chains): PDB file : Tito_1E7P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1E7P-query.scw PDB file : Tito_Scwrl_1E7P.pdb: