Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNNNNSPIGMIDSGLGGLSLFKHIREALPNEDIIYFADSKYVPYGNRESDWIVSRTTHLISNLVAHGKCKAIVIACNTMTAVAVETIRAQINVPLIS-IEPAVKPAVAMTVSKHIAVLATATTVKGKNLKSLIETYAQDIKVSLVPCIGLAEKIETGKAHTAEVKDYLKNILAPLVEQKVDTIILGCTHYPFVSDTIQEIVGRDIQIIEPSEAVTAQLIRQLNQYHLSSESPNEGNHIIWTSSDPLEVADVTFSLLSEKLSVKAVEL-- 1B74 Chain:A ((1-252)) -----MKIGIFDSGVGGLTVLKAIRNRYRKVDIVYLGDTARVPYGIRSKDTIIRYSLECAGFLKDKG-VDIIVVACNTASAYALERLKKEINVPVFGVIEPGVKEALKKSRNKKIGVIGTPATVKSGAYQRKLEEG--GADVFAKACPLFAPLAEEGLLEGEITRKVVEHYLKEF-KGKIDTLILGCTHYPLLKKEIKKFLG-DAEVVDSSEALSLSLHNFIKD-------DGSSSLELFFTDLSPNLQFLIKLILGRDYPVKLAEGVF

General information: TITO was launched using: RESULT: Template: 1B74.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1382 -108776 -78.71 -436.85 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -78.71 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.562

(partial model without unconserved sides chains): PDB file : Tito_1B74.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1B74-query.scw PDB file : Tito_Scwrl_1B74.pdb: