Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTQNLMCPVCRQRLELVSKTWRCEQGHSYDIAKQGYVNLHVVQHKHSKNPGDTPESVDARRAFLQGGYYQPLQQAVVHLLKD---LQAKMVLDIGCGEGYYTSAMQQVVE--QCIGVDIAKNAVQRAAKLNDKVTWVVGTGATLPVIDQSMDVCTSLFSPIPQTEILRVVKDDGYLIVVTSATDHLYAMREALFEQVNPHIPQKFVEQLQ-DLFELKEQQVIDAPLVLDQQALKNLIAMTPYAYKASPERRMQLEQKAHLQVTASFQIYLFQKRNKKAI 1P91 Chain:A ((2-268)) ----SFSCPLCHQPLSREKNSYICPQRHQFDMAKEGYVNLLPVQHKRSRDPGDSAEMMQARRAFLDAGHYQPLRDAIVAQLRERLDDKATAVLDIGCGEGYYTHAFADALPEITTFGLDVSKVAIKAAAKRYPQVTFCVASSHRLPFSDTSMDAIIRIYAPCKAEELARVVKPGGWVITATPGPRHLMELKGLIYNEVHLH----APHAEQLEGFTLQQSAELCYPMRLRGDEAVALLQMTPFAWRAKPEVWQTLAAKEVFDCQTDFNIHLWQRS-----

General information: TITO was launched using: RESULT: Template: 1P91.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1252 -42673 -34.08 -163.50 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -34.08 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.458

(partial model without unconserved sides chains): PDB file : Tito_1P91.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1P91-query.scw PDB file : Tito_Scwrl_1P91.pdb: