Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRGLYLITNDDPIQ--LLLEKLDAALATRQIAILQYRRKKIDKAEQPAEVEQIKQLCEKYQIPFVINDDLKLAAQFG-LGVHLGQSDGEITDAKSQLPEGVIIGRTCLNSLELAQKAI--ADGATYVAFGAVYATATKPEA--GNVGIEVIKQAAAQ------YDLPICAIGGLTVENSKPVIEA--------GADLCAVISDILGRSTAEIPARVQAWAQLFS 3NL6 Chain:A ((9-243)) DYSLYLVT-SGMIPEGKTLYGQVEAGLQNGVTLVQIREKDADTKFFIEEALQIKELCHAHNVPLIINDRIDVAMAIGADGIHVGQDDMPIPMIRKLVGPDMVIGWSVGFPEEVDELSKMGP--VDYIGVGTLFPTLT----KKAPMGTAGAIRVLDALERNNAHWCRTVGIGGLHPDNIERVLYQCVSSNGKRSLDGICVVSDIIASLD--AAKSTKILRGLI-

General information: TITO was launched using: RESULT: Template: 3NL6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 942 -18960 -20.13 -98.24 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -20.13 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_3NL6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3NL6-query.scw PDB file : Tito_Scwrl_3NL6.pdb: