Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVKILAVDMDGTFLNSKKQYNKARFLKQYEQLKQNNIRFVVASGNQLAKLVTYFPEI----N-HEIAFIAENGAHV-VDAGQELAFAHLSKEQFIEILNAIDPV-YTSKMVICGKQSAYVHSSMNAEDYAKVARYFEK--L--TVIDDFYALDDLVCKITFTAQENESFTIFEHFQKQSFVKDKVLVPVSSGFNFIDLILPDQHKAHGLKLLLQKWQVQPDQVVAIGDNNNDIQMIKAAGYGFAVEA----LKSVTPYTTANNEQEGALQVIDLVLQHQPPFA 4ZEX Chain:A ((27-295)) DEIKIIFTALDGTLLNSENKVS-EQNLESLIRAQEKGIKVVIATGRSIFSVENVIGEHVKKNRISLLPGIYMNGCVTFDEKGSRVIDRIMNNDLKMEIHEFSKQINISKYAIWFCLEKTYCFEIND-----CIREYMEVEALNPDVIEDNMLEGLTVYKVLFSLPENILENTLKLCREK---FSHRINVANTFQSYVELFHQHTNKFEGVKEICKYYNISLNNALAMGDGENDIEMLSGLTHSVGVHNASEKVKNSAAYVGPSNNEHAISHVLKTFCD------

General information: TITO was launched using: RESULT: Template: 4ZEX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1431 -36214 -25.31 -142.57 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -25.31 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.511

(partial model without unconserved sides chains): PDB file : Tito_4ZEX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ZEX-query.scw PDB file : Tito_Scwrl_4ZEX.pdb: