Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQSYSVIVVRSQEKKDALYELV-PQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVEGLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYPVFGMALGVPNQTHDVKPRLPLDNVVFEEEYQEQSTEAIQAYDRVQADYAGARAT-TSWSQRLAEQFGQAEPSSTRKNLEQKKLL 5UU6 Chain:C ((4-241)) MNSTIQTILGHRSIRKFTSQPIDKEQLETILQAGLAASSSSMLQVVSIVRVTDIEKRSQLAKFAGNQAYVESAAEFLVFCIDYQRHASINPDVQ----ADFTELMLIGAVDSGIMAQNCLLAAESMGLGGVYIGGLRNNAQQVDELLGLPQNTAILFGMCLGHPDQNPEVKPRLPAHVVVHENQYQDLNLDDIQAYDQTMQNYYANR--QSTWSQEVTSKLAGESRPHILPYLNGKGLA

General information: TITO was launched using: RESULT: Template: 5UU6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 936 -53274 -56.92 -230.62 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain C : 0.78 3D Compatibility (PKB) : -56.92 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.561

(partial model without unconserved sides chains): PDB file : Tito_5UU6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5UU6-query.scw PDB file : Tito_Scwrl_5UU6.pdb: