Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVMFTLKQFQYFIKIVEEGSFTAASEKLFIAQSALSRQMKLLEEEIDFLLFDRTDKRVKLTAAGEVFYKKIKDNLLYLNEIIDLSKSVSEGKNRQIKIAHSSSIV--VDNTKVQILKEVSLTQQLSFEINTLSSEQQILALLNGEIDIGLIRPPVRHTLDGINTLKLYEEPLMVAVHIDHAKFAK--SEKVYLKDLKDECFVSTPHAERG--GLSYLVANLCLAAGFTPQKASIQSRKISQLQLVAANLGVGIVPAEFQQILPANVKLIPLEDSLSLSEVLLVYRKDH-DEIIQHCAEQIHQMFLS 2H98 Chain:A ((89-293)) --------------------------------------------------------------------------------------------SQTLRIGYVSSLLYGLLPEIIYLFRQQ--NPEIHIELIECGTKDQINALKQGKIDLGFGRLKIT--DPAIRRIMLHKEQLKLAIHKHH-HLNQFAATGVHLSQIIDEPMLLYP--VSQKPNFATFIQSLFTELGLVPSKLTEIREIQLALGLVAAGEGVCIVPASAMDIGVKNLLYIPILDDDAYSPISLAVRNMDHSNYIPKILACVQEVF--

General information: TITO was launched using: RESULT: Template: 2H98.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1019 -12411 -12.18 -62.68 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -12.18 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.470

(partial model without unconserved sides chains): PDB file : Tito_2H98.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H98-query.scw PDB file : Tito_Scwrl_2H98.pdb: