Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIQEIRHPLIRHKLGLLRRADISTKNFRELAQEVTMLLTYEATKDLPVVDCEIEGWAGNVTTQRIA---GKKITIVPILRAGIGMLDGVLNLIPSAKVSVLGLERDEAT-------LEVRTYYKKLVPDVANRI--AMIIDPMLATGNSLVAAIDVLKASGCKDIRVMVLVAAPEGIAKVEAAHPDIQLYTASIDNGLNEHGYIVPGLGDAGDKIFGSVQKD 3G6W Chain:D ((2-216)) -PLYVIDKPITLHILTQLRDKYTDQINFRKNLVRLGRILGYEISNTLDYEIVEVETPLG-VKTKGVDITDLNNIVIINILRAAVPLVEGLLKAFPKARQGVIGASRVEVDGKEVPKDMDVYIYYKK-IPDIRAKVDNVIIADPMIATASTMLKVLEEVVKANPKRIYIVSIISSEYGVNKILSKYPFIYLFTVAIDPELNNKGYILPGLGDAGDRAFG-----

General information: TITO was launched using: RESULT: Template: 3G6W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1033 -40188 -38.90 -197.97 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain D : 0.77 3D Compatibility (PKB) : -38.90 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.520

(partial model without unconserved sides chains): PDB file : Tito_3G6W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3G6W-query.scw PDB file : Tito_Scwrl_3G6W.pdb: