Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTEKGVETMKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKKYLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAG-NTGALLAAG------LFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDL----GANAENKPEHLLQYGILGSFYARKVRGIGRPRVALLN----NGTEATKGS---EVTKKAYELLQNETSL-NFIGNVEARELLN----GVADVVVT-DGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEMDYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE 1YXO Chain:A ((99-275)) -------------------------------------------------------------------------------------TLTRAGQGCLDGHFAGMITAPVHKGVINEAGIPFSGHTEFLADLTHTAQ-VVM-MLATRGL--RVALATTHLPLREVADAISDERLTRVARILHADLRDKFGIAHPRILVCGLNPHAGEGGHLGREEIEVIEPCLERLRG--EGLDLIGPLPADTLFTPKHLEHCDAVLAMYHDQGLPVLKYK-------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1YXO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 497 -5625 -11.32 -36.76 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -11.32 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_1YXO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1YXO-query.scw PDB file : Tito_Scwrl_1YXO.pdb: