Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGYGHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQ-PILILNMVPYDALTVAVAHDLSVTAGTREWLQAAAAVLEKSKLE-TPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESRV--LEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPEL-PRYVHVSNSATALWHDETIGNMIRYGVAMYGLNPSGHALPEV-YPLQPALELVSELIQVKKLPAGEGIGYGETYITPEAEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTLIGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE 1BD0 Chain:A ((12-244)) -------VDLDAIYDNVENLRRLLPD-----DTHIMAVVKANAYGHGDVQVARTALEAGASRLAVAFLDEALALREKGIE-APILVLGASRPADAALAAQQRIALTVFRSDWLEEASALY---SGPF-PIHFHLKMDTGMGRLGVKDEEETKRIVALIE--RHPHFVLEGLYTHFATADEVNTDYFSYQYTRFLHMLEWLPS-RPPLVHCANSAASLRFPDRTFNMVRFGIAMYGLAPSPGIKPLLPYPLKEA------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1BD0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1229 -49349 -40.15 -217.39 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -40.15 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.485

(partial model without unconserved sides chains): PDB file : Tito_1BD0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1BD0-query.scw PDB file : Tito_Scwrl_1BD0.pdb: