Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKISTYENKKVLVLGLAKSGVS-AAKLLHELGALVTVNDGKPFDENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITEVELAYEVA--ECPIIGITGTNGKTTTTTMTGLLLNAGADQGI-ARLAGNIGYPASGVA---------------------QEAKSEDKIVMELSSFQLMGIT------DFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTEKDYLILNWNQSELQELAQR------TKARVLPFSTKEVLEDGVY---ADDYS--IYY-KKEKIMEISELGVPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKATNILATKMALSGFET----SKVVLLAGGLDR----GNTFDELIPSLKGIKAMVVFGQTKEK--LMDAGKKAG----IE-TIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVNRLK 3HN7 Chain:A ((0-485)) --------GMHIHILGICGTFMGSLALLARALGHTVTGSDANIYPPMSTQLE--QAGVTIEEGYLIAHLQ-PAPDLVVVGNAMKRGMDVIEYMLDTGLRYTSGPQFLSEQVLQSRHVIAVAGTHGKTTTTTMLAWILH-YA-GIDAGFLIG--GVPLVNTTDTNLQQVFAHSSYLGTEKDDSDNSVNTGYFVIEADEYDSAFFDKRSKFVHYRPRTAILNNLEFD------DLDAIQTQFHHMVRMIPSTGKIIMPAATISLEDTLAKGVWTPIWRTSVID----NSSDWQAELISADGSQFTVSFNDNKEATALVNWSMSGLHNVNNALVAIAAAYNIGVSVKTACAALSAFAGIKRRMELIGDVNDILVFDDF-AHHPTAITTTLDGAKKKLADRRLWAIIEPRSNTMKMGIHQDSLAQSATLADHTLWYEPTGLEWGLKEVIDNATIANPSIGSQQVLSSVDDIIKHICTHAKAGDAIVIMSNG------------------------

General information: TITO was launched using: RESULT: Template: 3HN7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2344 8866 3.78 22.00 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 3.78 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.480

(partial model without unconserved sides chains): PDB file : Tito_3HN7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HN7-query.scw PDB file : Tito_Scwrl_3HN7.pdb: