Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNPATQDAAAAEEESPVVCTAKKYIFDLHSYAWKESDCLIRIPRPHKGMGHGGMRVCYAVEDVDEEGAGTPMVAKMFRRNISDVVEKD-YFNEGAAQCMCEEFANNFNRIHLTNIHKP--NISFLQCYVVRIPRDSIPVASQKKRTGFFSYKTQDTGEVMFVMEPMLSGKFTKYNSNYGETYREDKKAALTSSEAKRRTEVFEAAEAFSHFTLVESGGSMLVCDLQGVNDFLTDPQIHTEDGKGLGMGNMGQEGIDKWIEKHECNEICRALGLQPLLGAVPSSTACAKEENLNLGLRAQLQSQNPVRLRDLVPLTKPLEEMTEAERIEYALKVSRLTD 5DYJ Chain:A ((105-275)) --------------------------------------------------------------------GTKFVLKLYKKEAEQQASRELYFEAVKMQMVCRDWGNKFNQ------KKPPKKIEFLMSWVVEL-IDRSPSSNGQ--------------PILCSIEPLLVGEFKKNNSNYG--------AVLTN----RST-----PQAFSHFTYELSNKQMIVVDIQGVDDLYTDPQIHTPDGKGFGLGNLGKAGINKFITTHKCNAVCALLDLDVKL-------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5DYJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 757 15665 20.69 93.24 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 20.69 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.502

(partial model without unconserved sides chains): PDB file : Tito_5DYJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DYJ-query.scw PDB file : Tito_Scwrl_5DYJ.pdb: