Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALL--------SKATR---QYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHA---VDRGHLLGYALIGGLDGFDASTSNPKNIAVQTAW--------ANQAQAEYSTGQNYYESKVRK--ALDQNKRVRYRVTLYYASNEDLVPSASQIEAK----SSDGEL---EFN-------------VLVPNVQKGLQLDYRTGEVTVTQ 2XH3 Chain:A ((48-249)) ------------------------------------------------------------------------------------------------------TVSSKLLPFTANYQLQLGELDNLNRATFSHIQLQDRHET------------------------SSWVMNRGHLVGYQFCGLND-------EPRNLVAMTAWLATGAYSGANDSNPE---GMLYYENRLDSWLALHPDFWLDYKVTPIYSGNE-VVP--RQIELQYVGIDSSGELLTIRLNSNKESIDENGVTTVILENSAPNINLDYLNGTAT---

General information: TITO was launched using: RESULT: Template: 2XH3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 566 43624 77.07 330.48 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 77.07 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.172

(partial model without unconserved sides chains): PDB file : Tito_2XH3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2XH3-query.scw PDB file : Tito_Scwrl_2XH3.pdb: