Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNNMHSQTTIAAIATP--PGRGGVGVIRLSGPKAYNIAQKLTQ---KNLPEAR--MAGFRKFYDTDGSIMDEGIVLCFPNPHSFTGEDVVELQGHGGPVIQNALLGRLFELGANAAKAGEFSMRAFENGKMDLVQAEAIADLIDATSQAAARSAVRSLQGAFSTKINTVLEKLIHLRLHVEAAIDFPEEEIDFLADGKILALLEDVQQSVHAVQTSARQGQLLREGLQVVIAGKPNAGKSSLLNALAGVERAIVTDIAGTTRDVLHEKISLNGLPITLTDTAGLRETGDVVEKEGIRRAIKEIEQADLLLLVYDLNQGDDPLKLAQEYFAEHIEPRRLMLIGNKCDLTGQSAEISDYQGFRHIT----VSAKQEMGVQGLVDAI--TAHAGFHPEEDTFIA-RTRHLDAMTRTQLYLAEAREQLVVFNAGELVAESLRLAQNALGEITGDFSADDLLGKIFGSFCIGK 3GEH Chain:A ((2-462)) -SHMAITGTIAAIATAIVPQQGSVGIVRVSGSQAIAIAQTLFDAPGKQVWESHRILYGYIRHPQTR-QIVDEALLLLMKAPRSYTREDVVEFHCHGGIIAVQQVLQLCLESGARLAQPGEFTLRAFLNGRLDLTQAESIADLVGARSPQAAQTALAGLQGKLAHPIRQLRANCLDILAEIEARIDF-EEDLPPLDDEAIISDIENIAAEISQLLATKDKGELLRTGLKVAIVGRPNVGKSSLLNAWSQSDRAIVTDLPGTTRDVVESQLVVGGIPVQVLD--------------------QAANTADLVLLTIDAATG---WTTGDQEIYEQVKHRPLILVMNKIDLV-EKQLITSLEYPENITQIVHTAAAQKQGIDSLETAILEIVQTGKVQAADMDLAINQRQAAALTQAKMSLEQVQATITQQLPLDFWTIDLRGAIQALGEITGEEVTESVLDRIFSRFCIGK

General information: TITO was launched using: RESULT: Template: 3GEH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2000 -1808 -0.90 -4.23 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -0.90 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.452

(partial model without unconserved sides chains): PDB file : Tito_3GEH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3GEH-query.scw PDB file : Tito_Scwrl_3GEH.pdb: