Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSSYRQQLQAKIDRITTQFSEFTPPTLEVFESPEQHFRMRAEFRIWHTENDMFYAMFERNDDGKQKTVVRIDEFPIADKSINDLMPLLLAELKANSLLSQRLFEVDFLATLSGEMLVTLIYHRKLNQEWEQAAKALAEKLNIKIMGRSRGQKIVIGDDFVVEEFELLNRSFKYKQIESSFTQPNAQVCKKMLQWACDAAEGSKKHLLELYCGNGNFTLPLSLKFERVLATELAKSSVYAAQWNIEQNQIDNIQVARLSAEEFTQAYQGEREFRRLQEADIDIQSYDFGTVFVDPPRAGIDDETLKLL--QGFERIIYISCNPDTLYENLKTLTQTHRVTKFALFDQFPYTHHVESGVLLEKI 2JJQ Chain:A ((268-419)) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NSFFQTNSYQAVNLVRKVSELVEGEK--ILDMYSGVGTFGIYLAKRGFNVKGFDSNEFAIEMARRNVEINNVDA-------------------EFEVASDREVSVKGFD--TVIVDPPRAGLHPRLVKRLNREKPGVIVYVSCNPETFARDVKML--DYRIDEIVALDMFPHTPHVE--------

General information: TITO was launched using: RESULT: Template: 2JJQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 737 -57005 -77.35 -380.03 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -77.35 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.520

(partial model without unconserved sides chains): PDB file : Tito_2JJQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2JJQ-query.scw PDB file : Tito_Scwrl_2JJQ.pdb: