Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSNVDQRPIILTGDRPTGQLHLGHFVGSLRSRVGLQDS--HHQHLLLADAQALTDN-ADNPDKVRRNILEVALDYLAVGIDPTKTTICVQSCLPALNELTMLYLNFVTVARLERNPTIKSEIQMRGFERDIPAGFLCYPVAQAADITAFKATVVPVGEDQIPMIEQTNEIVRRVNRQIGQDLLPECKALLSNMA-RLPGFDGKAKMSKSLGNTIVLNASDKDIKKAVNAMYTDPNHLRIEDPGQVEGNIVFTYLDAFDPNKEEVEELKAHYRRGGLGDGTVKKRLEGVLKELITPMRERREELAKDPDYIMDVLRQGTDKCRIITQQTLDEVKDGLGLFKF 2EL7 Chain:A ((4-328)) ---------VLSGIQPSGEIHIGNYLGAIKQWVAIGEKLGRDAFFCIVDYHALTNPLAYDPSTLAQRTFEAALVNIAAGLDPEKVTLFVQSHVPEHTELSWVFTTLTPLGDLTRMTQFKDKASK---QETVWSGLLMYPVLQAADILIYKADTVPVGEDQVQHIELTREIARRFNHLFGETF-PEPQALLNPEAPRVPGIDGKAKMSKSLGNTIGLLEPEESIWQKIQHLPDDP-------------TILFTYLSYFAP-KDLVEALKEEYRKAGVGTYVVKRILFDHLMEALRPIRERAEALKKDPDYVMDALLEGAKRARAVAQATMEEVREKVGLL--

General information: TITO was launched using: RESULT: Template: 2EL7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1424 -35462 -24.90 -115.14 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : -24.90 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.592

(partial model without unconserved sides chains): PDB file : Tito_2EL7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2EL7-query.scw PDB file : Tito_Scwrl_2EL7.pdb: