Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFY 2QMS Chain:A ((19-100)) WFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFH

General information: TITO was launched using: RESULT: Template: 2QMS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 295 -56385 -191.14 -687.62 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.95 3D Compatibility (PKB) : -191.14 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.95 QMean score : 0.733

(partial model without unconserved sides chains): PDB file : Tito_2QMS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QMS-query.scw PDB file : Tito_Scwrl_2QMS.pdb: