Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRGHNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNVVYGAKNQKFGAAGSLYDILTDERLNHRVEVETGILEDECAAIMQDFFRNRRKK 1WWR Chain:A ((23-167)) -------KEYFLKVALREAKRAFEKGEVPVGAIIVKEGEIISKAHNSVEELKDPTAHAEMLAIKEACRRLNTKYLEGCELYVTLEPCIMCSYALVLSRIEKVIFSALDKKHGGVVSVFNILDEPTLNHRVKWEYYPLE-EASELLSEFFKKLR--

General information: TITO was launched using: RESULT: Template: 1WWR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 815 -103210 -126.64 -711.79 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.84 3D Compatibility (PKB) : -126.64 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.577

(partial model without unconserved sides chains): PDB file : Tito_1WWR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WWR-query.scw PDB file : Tito_Scwrl_1WWR.pdb: