Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVFIAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVS--VDVTDREVILVDDVLYTGRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTELDDQDRVLITEEA 1XZ8 Chain:A ((1-179)) MQKAVVMDEQAIRRALTRIAHEIIERNKGIDGCVLVGIKTRGIYLARRLAERIEQIEGASVPVGELDITLYRD------------VPFPVTERNVILVDDVLFTGRTVRAAMDAVMDLGRPARIQLAVLVDRGHRELPIRADFVGKNVPTSRSELIVVELSEVDGIDQVSIHEK-

General information: TITO was launched using: RESULT: Template: 1XZ8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 824 -61312 -74.41 -383.20 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain A : 0.87 3D Compatibility (PKB) : -74.41 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.87 QMean score : 0.649

(partial model without unconserved sides chains): PDB file : Tito_1XZ8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XZ8-query.scw PDB file : Tito_Scwrl_1XZ8.pdb: