Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGLAANMIGVQKRVIIFNLGL---VPVVMFNPVLLSFEGSYEAEEGCLSLVGVRS-TKRYETIRLAYRDSKWQEQTITLTGFPAQICQHELDHLEGRII 3QU1 Chain:A ((33-145)) -------------------------LIDDLLDTLYAT-DNGIGLAAPQVGREEAIVVIDLSDNRDQPLVLINPKVVSGSNKEMGQEGCLSVPDYYADVERYTSVVVEALDREGKPLRIETSDFLAIVMQHEIDHLSGNL-

General information: TITO was launched using: RESULT: Template: 3QU1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 486 -26786 -55.11 -245.74 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -55.11 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.444

(partial model without unconserved sides chains): PDB file : Tito_3QU1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QU1-query.scw PDB file : Tito_Scwrl_3QU1.pdb: