Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVPLKGAR-DGHDFIETAFENGAAVTLSEKEVSNHPYI-LVDDVLTAFQSLASYYLEKTTVDVFAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAPA-DPIVEDYLPIDKKVVRFG-QGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNATNAM-IASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLD-IVIFYGEDIAQLAQLASQMFPIGHVYYFKKTEDQDQF-EDLVKQVKESLGAHDQILLKGSNSMNLAKLVESLENEDK 3ZL8 Chain:A ((11-422)) ------------------------------LNSKEVREGDVFVAVKGKRFDGHDFIDEALRNGAYAIIAERKTVNSDRIFLVESSVDTLAKLAREKLGNFSGTVVGVTGSSGKTTTKEILYNLLKNKRSVFKTPGNMNTEYGLPLSILNDYKGEEILVLEMAASRPGDIAHLCKIAPPDVAVLLNVGSAHLEFFGTRERIMETKMEIIKHSKENAIAVTLFDDPDLRKEVPRYRNTLFFGKEGGDSVLKDWWYYEGSTIAEFEAFDSLFTVKLSGYWNGGQLLNIAASLCVMRTLGETVDIFDLASLKTVPGRFNVRE-KKGVLIVDDTYNASPEAFQTSIEALLRFP----GKKFAVVGAMKELGERSKEFHEELGERL--NVLDGVYVFLSEPEAEWIKSKKIIL---------KSDDPEKIAKDLATRVKKG----DVVLFKASRAVRIERVLEMFEKE--

General information: TITO was launched using: RESULT: Template: 3ZL8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2395 79281 33.10 195.76 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : 33.10 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.414

(partial model without unconserved sides chains): PDB file : Tito_3ZL8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ZL8-query.scw PDB file : Tito_Scwrl_3ZL8.pdb: