Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGVDISSTSVKLLELSVKNGKYWVESYALMPLPENSVVEKNILNPEAVAEALERAMNLANPQTTHAAIAVPTSTVIHKTIEMDADMSDDEREVQIRVDAEQYIPFPLDEVSLDFEVLPDRLANPNRVNVLLVATRTENVETRVEVLELADLNPKLADVESYAVERTFSVFADSLPIGANTIGILDIGHTMTTLSVMQNGKIIYTREQVFGGKQLTLEIQSRYGLSLEEASRAKKDRSLPDDYEIEVLDPFLDAVVQQAARSLQFFFSSSQFNEIDHILLAGGNANIPGLAKLLQQKLGYRVTIA-NPFLQMGFSPQVDVQKIENDASSLMVACGLALRSFD 3H1Q Chain:A ((136-262)) -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGINDGIVVDIGGGTTGIAVIEKGKITATFDEPTGGTHLSLVLAGSYKIPFEEAETIKKDFSRHREIM-RVVRP----VIEKMALIVKEVIKN--YDQTLPVYVVGGTAYLTGFSEEFSRFLGKEVQVPIHPLL--------------------------------

General information: TITO was launched using: RESULT: Template: 3H1Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 562 -80868 -143.89 -641.81 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -143.89 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.594

(partial model without unconserved sides chains): PDB file : Tito_3H1Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3H1Q-query.scw PDB file : Tito_Scwrl_3H1Q.pdb: