Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLQAVYLTPIELHQTPDWSDRPYNIHRDPLWKTEKQGKEFDDVWFYHCDHLGTPQEMTDHTGAIIWKAEYKAWGECKAEKAKSNFFENSEIISNNIRFQGQYFDEETGLHYNRYRYYSPYVGRFVSKDPIGLLGGSNNYAYAPSPTEWVDPLGLSCQKIPKGFKSFGQLKQFGQAMQAGFSKLGFKGATMYMQGSAHSGRSFETGKAFDDGRVSDFDIAVVQPELFEKAKKMGIAKGNRTLPIEINSVEANKLGINGVLQKMSKLAGGRDVNVMIFDSPESAKAKAEGTRIPANCM 3QOY Chain:A ((113-140)) ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDFDVAIATPEMMPKVAKLGRILGPRGL-------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3QOY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 37 -4777 -129.09 -170.59 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.55 3D Compatibility (PKB) : -129.09 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.55 QMean score : 0.329

(partial model without unconserved sides chains): PDB file : Tito_3QOY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QOY-query.scw PDB file : Tito_Scwrl_3QOY.pdb: