Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYTIMEIINYLFGGISMKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKYHTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQE----LIGKMNTKPI-IIHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQKAAAYVQKLFM--NDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMTRGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLENMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMENEFSLR 1JDJ Chain:A ((17-343)) -------------------KAVVFGSGAFGTALAMVLSKKCREVCVWHMNEEEVRLVNEKRENVLFLKGVQLASNITFTSDVEKAYNGAEIILFVIPTQFLRGFFEKSGGNLIAYAKEKQVPVLVCTKGIERSTLKFPAEIIGEFLPSP---LLSVLAGPSFAIEVATGVFTCVSIASADINVARRLQRIMSTGDRSFVCWATTDTVGCEVASAVKNVLAIGSGVANGLGMGLNARAALIMRGLLEIRDLTAALGGDGSAVFGLAGLGDLQLTCSSELSRNFTVGKKLGKGLPIEEIQR---AVAEGVATADPLMRLAKQLKVKMPLCHQIYEIVYKKKNPRDALADLL-------------

General information: TITO was launched using: RESULT: Template: 1JDJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1908 -88887 -46.59 -280.40 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.78 3D Compatibility (PKB) : -46.59 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.550

(partial model without unconserved sides chains): PDB file : Tito_1JDJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JDJ-query.scw PDB file : Tito_Scwrl_1JDJ.pdb: