Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETALGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKDLNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQREDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK 3FB4 Chain:A ((1-212)) MNIVLMGLPGAGKGTQAEQIIEKYEIPHISTGDMFRAAIKNGTELGLKAKSFMDQGNLVPDEVTIGIVHERLSKDDCQKGFLLDGFPRTVAQADALDSLLTDLGKKLDYVLNIKVEQEELMKRLTGRWICKTCGATYHTIFNPPAVEGICDKDGG-ELYQRIDDKPETVKNRLDVNMKQTQPLLDFYSQKGVLKDIDGQQDIKKVFVDINDLL--

General information: TITO was launched using: RESULT: Template: 3FB4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 980 -86090 -87.85 -406.08 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.93 3D Compatibility (PKB) : -87.85 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.93 QMean score : 0.560

(partial model without unconserved sides chains): PDB file : Tito_3FB4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FB4-query.scw PDB file : Tito_Scwrl_3FB4.pdb: