Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEVFQTIINYVLNL---GSAIFVPLIILILGLLAGMKLKKAFMSALTLGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASI-----TWSWSYAFIFFAVTIGVNFVLLLFNW-T--KTLNVDMWNVWGKALTAYLVYYVS-GSLAAGFLTAMVQV-ILELKLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDK-IPALNK-RADTNALKKK--IGIFSENSVMGFII-GLGLGFA-------AAYG-------VSGSLNLAIQTATALSLFPMISKMFMQSLSPLADAMSEFMKKRFKDREVYIGLDWPILAGR-SEIWVTAILLVPVFIGYAII-LPGNQVLPLAGII-NYSIAVG--GLLL-------TGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKKGQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAELQK 4RP9 Chain:A ((6-403)) -----NIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKGTIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIDRMGDAYSW--VGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTIICTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQF-------ASWIAYKVAPFLGKKEESVEDLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVHWTVYILQTGFSFAVAIFIITQGVRMFVAE---LSEAFNGISQRLIPGA--VLAIDCAAIYSFAPNAVVWGFMWGTIGQLIAVGILVACGS-SILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEIFGCVWAVKLTG-------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4RP9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1563 -207052 -132.47 -584.89 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -132.47 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.372

(partial model without unconserved sides chains): PDB file : Tito_4RP9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4RP9-query.scw PDB file : Tito_Scwrl_4RP9.pdb: