Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence EGDYYFTPPPATEKCAYTIYRVASKNGLKAL--VREGD------YMAYKNWDQEIHGVQVHFDGEC-NPKYKSDVYVFKKGVREEKHIWLSPPPNKSSGVH 1WM2 Chain:A ((12-89)) -----------TENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQL----EMEDEDTIDVFQQ--------

General information: TITO was launched using: RESULT: Template: 1WM2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 223 3740 16.77 54.20 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 16.77 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.293

(partial model without unconserved sides chains): PDB file : Tito_1WM2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WM2-query.scw PDB file : Tito_Scwrl_1WM2.pdb: