Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKATQSKAWTTVQIARHPERPQ-FLDYVGEIFTE--FDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEGYRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGV----ADRVIMLSHSIYSVISPEGCASILWKTAEK-A--------A--------QASE-A-LGLTADKLQSLGIVEYVVDEGEGAHLDPERVMQNLKVVLKQALDELLPMDANERCEARYQRLMKFGSENLGMAS 4Q0G Chain:C ((288-518)) ---------------PPDPRVPYDVHEVVVRIVDGSEFSEFKAK--YG--KTLVTAFARVHGHPVGIVANNG-------------VLFSESALKGAHFIELCDKRKIPLLFLQNIAGFMVGRDYEAGGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVRGEQLSAAGTPWSPDEEEAFKAPIRAQYEDQGNPYYSTARLWDDGIID-P-----------ADTRTVVGLALSLCAHAP------------------------

General information: TITO was launched using: RESULT: Template: 4Q0G.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 966 -31461 -32.57 -153.47 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain C : 0.72 3D Compatibility (PKB) : -32.57 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.538

(partial model without unconserved sides chains): PDB file : Tito_4Q0G.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4Q0G-query.scw PDB file : Tito_Scwrl_4Q0G.pdb: