Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------------------------SSGSVGSTSPERP-VSP-GS----FDEHEG-----DQRPCKVTIEMGVS-PGGLFRQLYGSDYATRGGTVNINQYQCTVDVMCKNPSCPGLPARWEVTSFDKTKQRETHNQPAGGSVWAV-----GKKHDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1JJU Chain:B ((1-337)) RDYILAPARPDKLVVIDTEKMAVDKVITIADAGPT-PMVPMVAPGGRIAYATVNKSESLVKIDLVTGETLGRIDLSTPEERVKSLFGAALSPDGKTLAIYESPVRLE----LTHFEVQPT--RVALYDAETLSRRKAFEAPRQITMLAWARDGSK--LYGLGRDLHVMDPEAGTLVEDKPIQSWEAETYAQPDVLAVWNQHESSGVMATPFYTARKDIDPADPTAYRTGLLTMDLETGEMAMREVRIMDVFYFSTAVNPAKTRAFGAYNVLESFDLEKNASIKRVPLPHSYYSVNVSTDGSTVWLGGALGDLAAYDAETLEKKGQVDLPGNASMSLASVRLFTRDE

General information: TITO was launched using: RESULT: Template: 1JJU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 485 29182 60.17 277.92 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.55 3D Compatibility (PKB) : 60.17 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.55 QMean score : 0.150

(partial model without unconserved sides chains): PDB file : Tito_1JJU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JJU-query.scw PDB file : Tito_Scwrl_1JJU.pdb: