Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVTMQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHIIGLCKKQIRRMSLYPILIIVSRDSKV-IDDYKNLDIAY--VD---CTQ--CSNNFETALHVKNILKLLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWTYSMGDAFICVSETMKKRLESIIKNKKIVAINNGINVSNSDLDVV---GVQDFKKEFCIPNNKKIICYVGRLDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSM---------WAALKEKICHLKCRDNFRLLGEIYPAT--IVYQISDLLYIPSDTEGIPMCVLESMSQGTSVLASNVGGLSEIIEHRVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVETMRVYDELLEKSSHG 2X6R Chain:A ((37-414)) ------------------KLKGRSFVHVNS------TSFGGGVAEILHSLVPLLRSIG--IEARWFVIEGPTEFFNVTKTFHNALQGNESLKLTEEMKELYLNVNRENSKFIDLSSFDYVLVHDPQPAALIE---FY----EKKSPWLWRCHIDLSSPN-REFWEFLRRFVEKYDRYIFHLPEYVQPELD----RNKAVIMPPSIDPLSEKNVELKQTEILRILERFDVDPEKPIITQVSRFDPWKGIFDVIEIYRKVKEKIPGVQLLLVGVMAHDDPEGWIYFEKTLRKIGEDYDVKVLTNLIG-VHAREVNAFQRASDVILQMSIREGFGLTVTEAMWKGKPVIGRAVGGIKFQIVDGETGFLVR--DANEAVEVVLYLLKHPEVSKEMGAKAKERVRKNFIITKHMERYLDILNSL-------

General information: TITO was launched using: RESULT: Template: 2X6R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1824 -13053 -7.16 -36.67 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -7.16 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.462

(partial model without unconserved sides chains): PDB file : Tito_2X6R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2X6R-query.scw PDB file : Tito_Scwrl_2X6R.pdb: