Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVYYPQPVDNLVNKRSCKRRRYITMKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMDGARGEGA--QKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGYAGDPLWQKVNLDK----L-GTEAELN-------------YLQHGDPSGTIFSIGEADVSIRPGWFYHEDQ--DPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERPYEFATYRNELYKEDLALGAEVSGPALSADFDCRHLTDGLETSSWASDAD-LPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVD-GVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKTPGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSRSSSSLEAKISIQPGTGVHGVAYQDEIYALAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS 3UES Chain:B ((13-477)) ----------------------------YLANVRPSSRQLAWQRMEMYAFLHFGMNTMTDREWGLGHEDPALFNPRNVDVDQWMDALVAGGMAGVILTCKHHDGFCLWPSRLTRHTVASSPWREGKGDLVREVSESARRHGLKFGVYLSPWDRTEESYG--KGKAYDDFYVGQLTELLTQ-----YGPIFSVWLDGANGEGKNGKTQYYDWDRYYNVIRSLQPDAVISV-CGPDVRWAGNEAGHVRDNEWSVVPRRLRSAELT-------TTVSSQDDDLGSREAVAGYGDNVCWYPAEVDTSIRPGWFYHQSEDDKVMSADQLFDLWLSAVGGNSSLLLNIPPSPEGLLAEPDVQSLKGLGRRVSEF-REALASV-RCEARTSSASAAAAHLVDGNRDTFWRPDADDAAPAITLTLPQPTTINAIVIEEAIEHGQRIEHLRVTGALPDGTERVLGQAGTVGYRRILRFDDVEVSSVTLHVDGSRLAPMISRAAAVR--------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3UES.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2350 -42180 -17.95 -98.55 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain B : 0.71 3D Compatibility (PKB) : -17.95 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_3UES.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UES-query.scw PDB file : Tito_Scwrl_3UES.pdb: