Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLYATQDEKKQAAAKAALKHLPKGGILGVGTGSTVNFLIDLLPELQLEAAVASSQATADRLKKLGIEVVDMNHVVSLDAYVDGADEIDRHMHMIKGGGAALTREKIVASIAKKFVCIVDDSKWVDQLGRDFPLPVEVIPMARSAVARKLVSLGGDPVYREGVVTDNGNVILDVFNLNILNAIDLEKTINNIPGVVTNGIFALNP-ATIAIVATNDGIEERTAQ 1O8B Chain:A ((23-217)) --------------------------IVGVGTGST-------------EGAVSSSDA------------FDLNEVDSLGIYVDGADEINGHMQMIKGGG-ALTREKIIASVAEKFICIADASKQVDILG-KFPLPVEVIPMARSAVARQLVKLGGRPEYRQGVVTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFAN-RGADVALIGTPDGVKTI---

General information: TITO was launched using: RESULT: Template: 1O8B.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 924 -97634 -105.66 -588.15 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : -105.66 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.456

(partial model without unconserved sides chains): PDB file : Tito_1O8B.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1O8B-query.scw PDB file : Tito_Scwrl_1O8B.pdb: