Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------------------------------------MEEKKMKRFVRMGIDVGGTHTKAVAI-------DNATHEIIGKSS-------VKTTH--DDVRGVA---------AGVVQSFQNCLRENNISP-EDVVFVAHSTTQATNALI---EGDVAKVGVI-------GMAKGGLE------------------------GFLAKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNV--------------------------DRVSETISS-LER----ERAEVL--------VSSMAF-GVDNGEPERVVYEAASVKSIPTTMASDITK----------LYGLTRRTRTAAINASILPKMLDTATSTEDSVR----------EAGVNVS-LMIMRG-DGGVMEINEMKKRPVLTMLSGPAASVMG--------SLM------YLRASNGVYFEVGGTTTNIGVI--------KNGRPAIDYS----------IVGGHPTYISSLDVRVLGVA------------GGS----MVRA-NQSGIID-----------VGPRSAHIAGL-------------DYAVFTETEKIKGPKVEFFSPKEGDP--ADYVKVVMEDGEEVTITNTCAANVLG-----LVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEK-SYA-KIEPVILELADKYHLEKD--QISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSI--GVALAMVRDVVERIIPS----PSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVT-------AIATGST-EVKATDL-------TKEITTEEALELAAEDMRLNKNEV------------CLLENTPFFYVCGEQNRSKNAGSLRIID------QKGFIKVQRGHASCM--KTTAANYMTAVEQLWEDMAVYQTELIARPEF--------YLCLG----------ARVSDFTATDLEQLQLLMDLEVS-------TMEPEEEVIV-VAG---NIKQT---------------------------- 5B7I Chain:A ((4-1082)) SEFMNILLVSQCEKRALSETRRILDQFAERRGERTWQTPITQAGLDTLRRLLKKSARRNT-AVACHWIRGRDHSELLWIVGDASRFNAQGAVNDWHSAEDIRLLTVMAALFHDIGKASQAFQAKLR-NRGKPMADAYRHEWVSLRLFEAFVGPGSSDEDWLRRLADKRETGDAWLSQLARDDRQSAPPGPFQKSRLPPLAQAVGWLIVSHHRLPNGDHRGSASLARLPAPIQSQWCGARDADAKEKAACWQFPHGLPFASAHWRARTALCAQSMLERPGLLARGPALLHDSYVMHVSRLILMLADHHYSSLPADSRLGDPNFPLHANTDRDSGKLKQRLDEHLLGVALHSRKLAGTLPRLERQLPRLARHKGFTRRVEQPRFRWQDKAYDCAMACREQAMEHGFFGLNLASTGCGKTLANGRILYALADPQRGARFSIALGLRSLTLQTGQAYRERLGLGDDDLAILVGGSAQELLAENSHVHFAGTLEDGPLREWLGGNSAGNRLLQAPILACTIDHLMPASESLRGGHQIAPLLRLMTSDLVLDEVDDFDIDDLPALSRLVHWAGLFGSRVLLSSATLPPALVQGLFEAYRSGR-EIFQRHRGAPGRATEIRCAWFDEFSSQSSAHGAVTSFSEAHATFVAQRLAKLEQLPPRRQAQLCTVHAAGEARPALCRELAGQMNTWMA------DLHRCHHTEHQGRRISFGLLRLANIEPLIELAQAI-LAQGAPEGLHVHLCVYHSRHPLLVRSAIERQLDELLKRSDDDAAALFARPTLAKALQA--STERDHLFVVLASPVAEVGRDHDYDWAIVEPSSMR-SIIQLAGRIRRHRSGFSGEANLYLLSRNIRSLEGQNPAFQRPGFETPDFPLDSHDLHDLLDPALLARIDASPRIVEPFPLFPRSRLVDLEHRRLRALMLADDPPSSLLGVPLWWQTPASLSGALQTSQPFRAGAKERCYALLPDEDDEERLHFSRYEEGTWSNQDNLLRNLDLTYGPRIQTWGTVNYREELVAMAGREDLDLRQCAMRYGEVRLRENTQGWSYHPYLGFKKYN

General information: TITO was launched using: RESULT: Template: 5B7I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3779 40954 10.84 58.42 target 2D structure prediction score : 0.39 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 10.84 2D Compatibility (Sec. Struct. Predict.) : 0.39 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.178

(partial model without unconserved sides chains): PDB file : Tito_5B7I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5B7I-query.scw PDB file : Tito_Scwrl_5B7I.pdb: