Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKNNSRQFINGQRVAV-NVPALESIAAKDYEPTGYVFSQATLEEVDQAAQAAHNAFL--VYSQTTQEQRASFLEEIARQIEALGANLQEVASLETGLPLARLQGETGRVTGQLRLFAELLRRGDFYGARIDVALPERKPLPRVDLRQYKVGVGPVAVFGASNFPLAFSTAGGDTVAALAAGCPVVFKAHSGHMATAELVAEAIEKAIEVCGMPKGTFNMIFGGR--IGANLVEHSLIQAAGFTGSLEGGMALYNLAQSRPQPIPFFAEMSSVNPVVVLPEALHSRGEQIAQDTVASFNMGCGQFCTKPGLILGVKGPEFDRFITALAENTQK----------AVPQVMLNEGTLKSYRAGIDALINEAGFEIIASGQEP-----ELVSQAKAHLFKADQSVLLSGNPKLQHEVFGPMSIVIAVEDEATLLKGIEALGGQLTATIIGDENELSKAGELLDLLTRKAGRVLFNGFPTGVEVSDAMVHGGPFPATSDARGTSVGTGAIERFLRPVCFQNTPQVLLPDALKDSNPLQITRLVNGQLTQAQI 4QN2 Chain:A ((29-506)) ----SQRQYIDGEWVESANKNTRDIINPYNQEVIF-TVSEGTKEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESYADMDDIHNVFMYFAGLADK--DGGEMID----SPI--PDTESKIVKEPVGVVTQITPWNYPLLQAS--WKIAPALATGCSLVMKPSEITPLTTIRVFELM----EEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGSIETGKHIMKNAA--NNVTNIALELGGKNPNIIFDDADF---ELAVDQALNGGYFHAGQVCSAGSRILVQNS-IKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDV-AKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTS----MRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDIG--KAQRVANKL--KLGTVWINDFHPY---FAQAPWGGYKQ-SGI--GRELGKEGLEEYLVSKHILTN------------------------------

General information: TITO was launched using: RESULT: Template: 4QN2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2802 -2024 -0.72 -4.42 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -0.72 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_4QN2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QN2-query.scw PDB file : Tito_Scwrl_4QN2.pdb: