Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTYFELVRSMDVLEKITLPGKPKYLKLAEDFDFYELFKKIENQFSTCFIFESLGEEDYLSRHHIIGFDPEKFFYST-AVNELCVKDCTTNTILKYSCDHAYYKLREIVPQNIISKHYS-------------------------------------GGLVGFIGYNAISFFEPTLDVKNNEDFETFKFGLYLDGLVYDKLTGEIFYFYY-------KESRFNEILDILNSDI------NYNNNIKVQYLGNSVTKEEYENSVYKVKEYIKSGLIFQCEVGFKTDYIITGNHLEIYSKLREVNPSPHMYFMKFDDQKIIGASPELLFRL--HNKEMETFPLAGTAKRGK------DEIEDRKYARKLLNDPKEIAEHNMLVDLHRNDIGRVAQFGTVKVRKLMDIKRFSHIQHISSEIVGIIKEDEDMFSALASNFPAGTLSGAPKIEAMKIIDEIESSGRGVYGGAIGEFCFNGDCTFAIPIRSIFIKADRAYIQTCGGNVFDSNPEDEYIEIERKLAAMKTVLKNFEV- 1I1Q Chain:A ((5-516)) ------KPTLELLTCDAAYRE----------NPTALFHQVCGDRPATLLLESADIDSKDDLKSLLLVDSALRITALGDTVTIQALSDNGASLLPLLDTALPAGVENDVLPAGRVLRFPPVSPLLDENARLCSLSVFDAFRLLQGVVNIPTQEREAMFFGGLFAYDLVAGFEALPHLEAGNNCPDYCFYLAETLMVIDHQKKSTRIQASLFTASDREKQRLNARLAYLSQQLTQPAPPLPVTPVPDMRCECNQSDDAFGAVVRQLQKAIRAGEIFQVVPSRRFSLPCP-SPLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDAASRQIEIYPIAGTRPRGRRADGTLDRDLDSRIELDMRTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDRYSYVMHLVSRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIADAEGQRRGSYGGAVGYFTAHGDLDTCIVIRSALVENGIATVQAGAGIVLDSVPQSEADETRNKARAVLRAIATAHHA

General information: TITO was launched using: RESULT: Template: 1I1Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2315 15025 6.49 33.24 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : 6.49 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.368

(partial model without unconserved sides chains): PDB file : Tito_1I1Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1I1Q-query.scw PDB file : Tito_Scwrl_1I1Q.pdb: