Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVSTPCKLRGDDFMAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQEAQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILPAFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTLLPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKDIDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYLKLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLP----RITPHGFRHTHASLLLEAGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ 1AIH Chain:A ((4-161)) ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LAFLYERDIYRLLAECDNSRNPDLGLIVRICLATGARWSEAETLTQSQVMPY--KITFT--------------NTKS-KKNRTVPISDELFDMLPKK------------------RGRLFND----------AYESFENAVLR-AEIELPKGQLTHVLRHTFASHFMMNGGNILVLKEILGHSTIEMT-MRYAHFAPSHLESAVK---------

General information: TITO was launched using: RESULT: Template: 1AIH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 632 -71298 -112.81 -462.97 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -112.81 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.521

(partial model without unconserved sides chains): PDB file : Tito_1AIH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1AIH-query.scw PDB file : Tito_Scwrl_1AIH.pdb: