Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----------------------------------------------------------------------------------------------------------------------------------------------------------------------DTNSQQFIQVRRLPGH---VMGAVVRGSGCEFTLIKKNHKPMVQKIVDTSGDLDSNWKSIKIPFCGMTFNWAC-NPIDHGQWKFHSITKDGKHQYIDVNALQV------------------------------------------------------------------------------- 1GXR Chain:A ((1-337)) DYFQGAMGSKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQINTLNHGEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQ--FQGHTDGASCIDISNDGTKLWTGGLDNT--V-RSWDL-----REGRQLQQHDFTSQIFSLGYCP--TGE-WLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY

General information: TITO was launched using: RESULT: Template: 1GXR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 165 8581 52.00 99.77 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.53 3D Compatibility (PKB) : 52.00 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.53 QMean score : 0.340

(partial model without unconserved sides chains): PDB file : Tito_1GXR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GXR-query.scw PDB file : Tito_Scwrl_1GXR.pdb: