Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGGCTVKPQLLLLALVLHPWNPCLGADSEKPSSIPTDKLLVITVATKESDGFHRFMQSAKYFNYTVKVLGQGEEWRGGDGINSIGGGQKVRLMKEVMEHYADQDDLVVMFTECFDVIFAGGPEEVLKKFQKANHKVVFAADGILWPDKRLADKYPVVHI-GKRYL-NSGGFIGYAPYVNRIVQQWNLQDNDDDQLFYTKVYIDPLKREAINITLDHKCKIFQTLNGAVDEVVLKFENGKARAKNTFYETLPVAINGNGPTKILLNYFGNYVPNSWTQDNGCTLCEFDTVDLSA-----VDVHPNVSIGVFIEQPTPFLPRFLDIL-LTLDYPKEALKLFIHNKEVYHEKDIKVFFDKAKHEIKTIKIVG-----PEENLS---QAEARNMGMDFCRQDEKCDYYFSVDADVVLTNPRTL-KILIEQNRKIIA---PLVTRHGKLWSNFWG---ALSPDGYYARSEDYVDIVQGNRVGVWNVPYMANVYLIKGKTLRSEMNERNYFVRDKLDPDMALC----------------RNAREMGVFMYISNRHEFGRLLSTANYNTSHYNNDLWQIFENP-VDW--KEKYINRDYSKIFTENIVEQPCPDVFWFPIFSEKACDELVEEMEHYGKWSGGKHHDSRISGGYENVP-------TDDIHMKQVDLENVWLHFIREFIAPVTLKVFAGYYTKG-FALLNFVVKYSPERQRSLRPHHDASTFTI--NIALNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP-------- 5F7S Chain:B ((1-730)) --MITHRPRG-----IEHPYARSL--DQLYPAIPIAGQSLTIGATTSGP---------CSRMRCFVLWPEHEQVFD----MSPVNGWQTSI------PHLPDQD-----ATYYFEALTLDGRTETSESFPLT-------------PSHWSAEPVGHIDIDGDRFIPDSPLWLVSSAGTHRV--KFALRIEGDEHVVGFGERYDQL---------DQR-------GLRLDSVVFEQYKAQGKHHRT-YLPMPFAQVVNEAGR----AWGFHVETTRRTWYDVAATVSDRILIEVDLGFEAEKTPVVRVNTWSGSPTDVLNGFLDVAGRPAEMPEWIFGLWASGNEWNTQSLVMEQMDRHRNEGIPVSVVVIEAWSDEEGFTIFRDARYVPNQGQPHRGPD-----FTYPSDGAWPDPAGMIRELHERGIRVILWQIPLQKTDDDLGPEALAQGNALIASGHVVKEPDGTPY--KNRGWWFPNALMPDLSTEAGRQWWTEQ--RRYLVED-LDIDGFKTDGGEHAWGSDLRYEDGRRGDEGNNLYPVNYARAYGDLLRSAGKYPVTFSRSGFTGSQAHGLYWAGDEDSTWEAFRSSITAGITAGACGILYWGWDL---------------AGFSGPVPEAELYARAFAAATFMPIMQYHSEFHHHELPLRDRTPWNVAEQTGCGELIDLARHYTRVREALRPYLVAQTRQCLQTGKPLMRAMFYDHADDPEIWAHPRQYMLGD-ELLINPVTAPGATTWTTYLPEGQWEDYWSGEVSEGGHLVTRAVGWDIIPVYRRVG

General information: TITO was launched using: RESULT: Template: 5F7S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 3817 19391 5.08 30.20 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain B : 0.66 3D Compatibility (PKB) : 5.08 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.158

(partial model without unconserved sides chains): PDB file : Tito_5F7S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5F7S-query.scw PDB file : Tito_Scwrl_5F7S.pdb: