Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVKFSMEKENRGKNMAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSITVVRALNDLAKDGYIVRQQGKGTFVSRARKHK-LVEFSDIELFNAKDDKVTVLSI-ERGNKLVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINAN-YPNLEYYSSIYNRFKLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYSETYKRSDYYKIKFISCDRDH 3EDP Chain:A ((7-235)) ---------------KKPLFEVIASKIKDSINRDEYKTG--MPNETALQEIYSSSRTTIRRAVDLLVEEGLVVRKNGVGLYVQPKLTAQNILEMTGVMKN----LKKDIKDFYIRKAGKFYAEIFGMKENELVYSIKFVQKS-EHGATLDRLILPLGLYPDLQAKDFQ-IINIIELVN-SGKYKLF--ELEQELQLILAG-NEQIKNMHLNENDPVFKLSSVFYAE-NDMPIAIQYHYEDAESTKYVVDF-----

General information: TITO was launched using: RESULT: Template: 3EDP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1015 -4592 -4.52 -20.97 target 2D structure prediction score : 0.44 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -4.52 2D Compatibility (Sec. Struct. Predict.) : 0.44 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.382

(partial model without unconserved sides chains): PDB file : Tito_3EDP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EDP-query.scw PDB file : Tito_Scwrl_3EDP.pdb: