Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -MVRINKMNGKHVDIYIGKLNDFLNRKQHDFPDFRTFNEYKKQQI--QLIKNKLIAQKLEIAPTDLVFAKHEYGKPYLLDHA-LHFNHSHSQQYYALALSERVKDIGIDVEELDRKVRLDSLAQHAFHPDEYATWQSL--EQDREYWFKVWTTKEAVLKASGLGIRLDLNTLNTQAPPTNHGGLCSHELIGTFAYQNFVL-GNMILTVAWRSEQSCRGFQFPSIQIHSLDR- 1QR0 Chain:A ((1-228)) MKIYGIYMDRPLSQEENERFMTFISPEKREKCRRFYHKEDAHRTLLGDVLVRSVISRQYQLDKSDIRFSTQEYGKPCIPDLPDAHFNISHSGRWVIGAFDS--QPIGIDIEKTKPIS--LEIAKRFFSKTEYSDLLAKDKDEQTDYFYHLWSMKESFIKQEGKGLSLPLDSFSVRLHQDGQVSIELPDSHSPCYIKTYEVDPGYKMAVCAAHPDFPEDITMVSYEELLRAAA

General information: TITO was launched using: RESULT: Template: 1QR0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 973 50373 51.77 228.97 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 51.77 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.198

(partial model without unconserved sides chains): PDB file : Tito_1QR0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QR0-query.scw PDB file : Tito_Scwrl_1QR0.pdb: